3-Hydroxyphenazepam is a benzodiazepine with hypnotic, sedative, anxiolytic, and anticonvulsant properties. It really is a dynamic metabolite of phenazepam, as well as the energetic metabolite of the benzodiazepine prodrug cinazepam. In accordance with phenazepam, 3-hydroxyphenazepam has reduced myorelaxant properties, but is approximately equivalent generally in most other relation. Like other benzodiazepines, 3-hydroxyphenazepam behaves as an optimistic allosteric modulator of the benzodiazepine site of the GABAA receptor with an EC50 value of 10.3 nM. It's been sold online as a custom drug
Benzodiazepines are usually viewed as effective and safe for short-term use, although cognitive impairment and paradoxical results such as hostility or behavioral disinhibition once in a while appear. A minority of men and women can have paradoxical reactions such as worsened agitation or worry. Benzodiazepines are also associated with an increase of threat of suicide. Long-term use is questionable because of concerns about undesirable emotional and physical results, decreasing success, and physical dependence and drawback. Due to adverse effects from the long-term use of benzodiazepines, drawback from benzodiazepines often causes increased physical and mental health. Older people are at an elevated risk of experiencing both brief- and long-term undesireable effects, and for that reason, all benzodiazepines are outlined in the Beers Set of improper medications for elderly adults
Research chemicals are chemical compounds utilized by researchers for medical and technological research purposes. One feature of a study chemical is that it's for lab research only use; a research substance is not designed for real human or veterinary use. This differentiation is necessary on labels of research chemicals
Research chemicals are key in the introduction of book pharmacotherapies. Common medical lab uses use in vivo and canine testing to find out healing value, toxicology tests by deal research organizations to ascertain drug security, and research by drug ensure that you forensic toxicology labs for the purposes of analyzing human subjection. Many pharmacologically lively chemicals can be purchased online under the guise of "research chemicals," when the truth is they are simply untested artist drugs that are being used by purchasers taking good thing about lots of the substances' transitional or nonexistent legal position
This product is intended for research and forensic applications. Warning - this product is not for human or veterinary use.
3-Hydroxyphenazepam is an active metabolite of the novel psychoactive benzodiazepine phenazepam, which emerged in online drug markets in late 2011. Despite being a controlled substance in Europe, North America, and many countries in Asia, phenazepam has been encountered in the form of LSD mimic blotters and as counterfeit diazepam. This certified Snap-N-Spike® solution is suitable for use as a starting material in calibrators and controls for numerous GC/MS or LC/MS applications in forensic analysis, clinical toxicology and urine drug testing..
PubChem CID: 125820
Chemical Names: 3-Hydroxyphenazepam; 70030-11-4; 3-Oxyfenazepam; 7-bromo-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2h-1,4-benzodiazepin-2-one; 7-bromo-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one; 3-Hydroxyfenazepam More...
Molecular Formula: C15H10BrClN2O2
Molecular Weight: 365.611 g/mol
InChI Key: KRJKJUWAZOWXNV-UHFFFAOYSA-N
The energy of named 3-hydroxyphenazepam (dynamic phenazepam metabolite) after its intravenous and transdermal organization was contemplated. Biphasic motor of medication dissemination in the life form was uncovered; pharmacokinetic parameters and natural accessibility (1.32± 0.12 for the plasma and 1.21±0.10 for the mind) were resolved based on add up to radioactivity of the plasma and cerebrum.