An overview of Ephenidine


Ephenidine which is commonly called as EPE or NEDPA is kind of dissociative substance research chemical that belongs to diarylethylamine class. The Ephenidine has same struts as that of methoxphenidine and diarylethylamines. This research chemical is commonly referred to as "dissociative anesthesia". Ephenidine gives some prominent effects such as anesthesia, sedation, out-of-body states and hallucinations.


• Chemistry of Ephenidine


The chemical composition of Ephenidine shows that it belongs to the class of diarylethylamine. In its structure, it contains a basic skeleton of phenethylamine with substituted Rα in its phenyl ring. At the terminals of the molecule, an ethal chain is attached with amine RN of the phenethylamine. Although Ephenidine is not piperidine dissociative yet it has structural equivalency with diphenidineand MXP. This research chemical does not possess the substitution of piperidine, though Ephenidine shares diphenylethylamine skeleton with MXP diphenidine.


• Pharmacology of Ephenidine


Ephenidine is basically a contender of the NMDA receptor with Ki = 66.4 nM. N-methyl-D-aspartate is another type of research chemical that directly effects the excitatory neurotransmitter within the central nervous system (CNS). Contrary to Ephenidine, if NMDA ways are blocked, the user may feel immobilization or anesthesia, when it is taken at a high dose.


• Subjective effects of Ephenidine


Numerous subjective effects of usage of Ephenidine are determined on the basis of subjective effects index and personal experiences of PsychonautWiki contributors. So, its effects are compared with a grain of salt because it rarely affects the body. Although if Ephenidine is taken in heavy amount its effects will be enhanced. Similarly, if this research chemical is taken in form of higher doses it can cause serious illness even death.


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